Si entiendo bien tu inquietud lo que debes hacer es insertar un TabControl en un formulario y tres botones fuera del tab control y en el formulario programa el siguiente código:
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Public Class Form1
Private Sub CrearTextBox(ByVal EnDonde As Integer)
Dim NewTextBox As New TextBox
NewTextBox.Name = "TxtPrueba"
NewTextBox.Text = "como te quedó el ojo"
NewTextBox.Location = New Point(10, 10)
If EnDonde = 1 Then
TabControl1.TabPages(0).Controls.Add(NewTextBox)
Else
TabControl1.TabPages(1).Controls.Add(NewTextBox)
End If
End Sub
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Private Sub Button1_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button1.Click
CrearTextBox(1)
End Sub
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Private Sub Button2_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button2.Click
CrearTextBox(2)
End Sub
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Private Sub Button3_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button3.Click
Dim Var As New Control
Dim i As Integer
For i = 0 To TabControl1.TabCount - 1
For Each Var In TabControl1.TabPages(i).Controls
If TypeOf Var Is TextBox Then
Var.Text = ""
End If
Next
Next
End Sub
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End Class
Espero que te sirva el aporte
